Ideal for:

The 66-EI400 was designed to take advantage of the unique properties of ultramicro carbon fiber electrodes for in-vivo and in-vitro detection and quantitation of neurotransmitters such as dopamine and norepinephrine, as reported by Dr. Mark Wightman and others. Its high sensitivity, stability and dual-outputs are also attractive for controlling and monitoring in Scanning Electrochemical Microscopy (SECM). Both channels can be driven by an external signal source and input/output triggers are available to control remotely CV or other experiments. Variable slope triangle waves are formed digitally with two millivolt steps that have been shown to work well for fast scan in-vivo applications. Bipolar offset voltages are provided for both channels with choice of internal or external triggering to start scans.

Remote preampliers (head stages) are used to convert the low level currents to voltages suitable for amplification. This arrangement results in low noise and fast response, especially when used with a Faraday case to shield and minimize external noise. The gain factor for the head stages may be specified to fit the requirements of the experiment. A total gain range of one million is possible – going from high to low sensitivity. A low-pass cutoff filter is included in each of the current-to-voltage amplifiers. Implemented with a continuously variable cutoff frequency, these two pole filters permit optimal enhancement of the signal to noise ratio compared to a simple RC time constant filter.

A 3 ½ digit panel meter provides readout to set waveform parameters, bias potential offset, filter cutoff frequency and to monitor gain and outputs. At low scan rates, data can be recorded with a X-Y chart recorder, or at fast scans with a digital storage oscilloscope, and captured data can then be transferred to a computer for analysis.

Features:

Specifications:

Preamplifiers (specify at time of ordering):

Applications and Experiments